S1PR1

S1PR1
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	3V2W, 3V2Y
Dynodwyr
Cyfenwau	S1PR1, CD363, CHEDG1, D1S3362, ECGF1, EDG-1, EDG1, S1P1, sphingosine-1-phosphate receptor 1
Dynodwyr allanol	OMIM: 601974 HomoloGene: 1071 GeneCards: S1PR1
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• sphingolipid binding; • sphingosine-1-phosphate receptor activity; • G protein-coupled receptor activity; • signal transducer activity; • G protein-coupled receptor binding; • GO:0001948, GO:0016582 protein binding;
Cydrannau o'r gell	• integral component of membrane; • endosome; • bilen; • intrinsic component of plasma membrane; • Cellbilen; • membrane raft; • external side of plasma membrane; • nucleoplasm; • intracellular membrane-bounded organelle;
Prosesau biolegol	• actin cytoskeleton reorganization; • T cell migration; • G protein-coupled receptor signaling pathway; • heart trabecula morphogenesis; • positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway; • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; • sphingosine-1-phosphate receptor signaling pathway; • positive regulation of cell migration; • regulation of bone mineralization; • transmission of nerve impulse; • chemotaxis; • positive regulation of positive chemotaxis; • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity; • brain development; • regulation of cell adhesion; • cell adhesion; • angiogenesis; • neuron differentiation; • positive regulation of cell population proliferation; • endothelial cell differentiation; • negative regulation of stress fiber assembly; • regulation of bone resorption; • cell migration; • GO:0072468 signal transduction; • lamellipodium assembly; • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II; • cardiac muscle tissue growth involved in heart morphogenesis; • positive regulation of smooth muscle cell proliferation; • blood vessel maturation; • leukocyte chemotaxis; • cytokine-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologau
	1901
	n/a
	ENSG00000170989
	n/a
	P21453
	n/a
	NM_001400; NM_001320730
	n/a
	NP_001307659; NP_001391
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn S1PR1 yw S1PR1 a elwir hefyd yn Sphingosine-1-phosphate receptor 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1p21.2.^[2]

[1] "Human PubMed Reference:".

[2] S1PR1 - Cronfa NCBI

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